Stooped posture, shuffling gait, garbled speech, and tremors are symptoms of which disease?

The symptoms described—stooped posture, shuffling gait, garbled speech, and tremors—are characteristic of Parkinson's disease. This neurological disorder primarily affects movement and is often associated with a deficiency of dopamine in the brain.

The combination of a stooped posture and shuffling gait indicates a typical physical manifestation known as bradykinesia, which refers to slowness of movement. Tremors, particularly resting tremors, are also a hallmark sign of Parkinson's disease. Garbled or slurred speech can occur due to the muscle control difficulties that affect vocalization, which is common as the disease progresses.

In contrast, other diseases listed manifest different sets of symptoms. Alzheimer’s disease mainly involves memory loss and cognitive decline, and does not usually present with motor symptoms such as tremors or gait disturbances. Multiple sclerosis can lead to a variety of neurological symptoms, but the classic motor symptoms are not as distinctively associated with it as they are with Parkinson's. Huntington's disease typically features movement disorders that are more choreatic (involuntary, irregular movements) rather than tremors, along with significant cognitive decline. Therefore, the collection of symptoms provided in the question aligns specifically with Parkinson's disease.